This module will introduce the principles of team science and examine how team science can be used to enhance data-to-action initiatives. In lesson one, we will define team science, as we discuss how it is related to collective impact and CBPR. We will also review recommendations made by the National Academies Committee on the Science of Team Science for improving team science effectiveness. Lesson two will focus on the opportunities and challenges for team science in communities, as we further discuss incorporating community perspectives into team science research. We will also evaluate how to measure team science outcomes, as we consider how team science can add perspective and voice to data.